Isopropyl Alcoholไอโซโพรพานอล, Isopropanol, ไอโซโพรพิลแอลกอฮอล์, Isopropyl alcohol, ไอพีเอ, IPA ชื่อ ไอโซโพรพิลแอลกอฮอล์ (Isopropyl alcohol) ชื่ออื่น Isopropanol, IPA, 2-Propanol, Propan-2-ol, Dimethyl carbinol, Rubbing alcohol สูตรโมเลกุล C3H8O น้ำหนักโมเลกุล 60.1 CAS Number 67-63-0 UN Number 1219 ไอโซโพรพิลแอลกอฮอล์ (isopropyl alcohol) เป็นแอลกอฮอล์ชนิดหนึ่ง มีราคาถูก มีคุณสมบัติฆ่าเชื้อโรคได้ (disinfectant) จึงถูกใช้ในการทำความสะอาด บางครั้งอาจเรียกว่า แอลกอฮอล์เช็ดทำความสะอาด (rubbing alcohol) ก็ได้ สามารถ พบไอโซโพรพิลแอลกอฮอล์ในน้ำยาทำความสะอาด น้ำยาฆ่าเชื้อ สูตรต่างๆ ทั้งที่ใช้ในโรงพยาบาล ตามบ้าน และตามโรงงานต่างๆ โดยมักจะใช้ที่ความเข้มข้นประมาณ 70 % นอกจากนี้ยังใช้เป็นตัวทำละลาย (solvent) ในโรงงานอุตสาหกรรมต่างๆ อีกด้วย พิษของแอลกอฮอล์ชนิดนี้จะทำให้เกิดอาการเมาได้เหมือนพิษของเอทิลแอลกอฮอล์ สามารถกดสมองและกดการหายใจได้อย่างรุนแรง แต่มักไม่ก่อภาวะเลือดเป็นกรดอย่างรุนแรง (high gap metabolic acidosis) แบบเมทิลแอลกอฮอล์, ไอโซโพรพานอลเป็นสารในตระกูลแอลกอฮอล์ ไม่มีสี มีกลิ่นเฉพาะตัว ระเหยได้ง่าย ใช้ผสมในน้ำยาล้างเล็บ กาว น้ำมันชักเงา สี และใช้เป็นยาฆ่าเชื้อโรค เป็นสารตั้งต้นสำหรับผลิตอะซีโตน, Isopropyl alcohol is a chemical compound with the molecular formula C3H8O or C3H7OH. It is a colorless, flammable chemical compound with a strong odor. It is the simplest example of a secondary alcohol, where the alcohol carbon atom is attached to two other carbon atoms sometimes shown as (CH3)2CHOH. It is a structural isomer of propanol. Isopropyl alcohol is denatured for certain uses, in which case the NFPA 704 rating is changed to 2,3,1. Isopropyl alcohol is miscible in water, alcohol, ether and chloroform. It will dissolve ethyl cellulose, polyvinyl butyral, many oils, alkaloids, gums and natural resins.[3] It is insoluble in salt solutions. Unlike ethanol or methanol, isopropyl alcohol can be separated from aqueous solutions by adding a salt such as sodium chloride, sodium sulfate, or any of several other inorganic salts, since the alcohol is much less soluble in saline solutions than in salt-free water. The process is colloquially called salting out, and causes concentrated isopropyl alcohol to separate into a distinct layer. Isopropyl alcohol forms an azeotrope with water, which gives a boiling point of 80.37 oC and a composition of 87.7 wt% (91 vol%) isopropyl alcohol. Water-isopropyl alcohol mixtures have depressed melting points. It has a slightly bitter taste, and is not safe to drink. Isopropyl alcohol becomes increasingly viscous with decreasing temperature. At temperatures below −70 °C Isopropyl alcohol resembles maple syrup in viscosity. Isopropyl alcohol has a maximum absorbance at 204 nm in an ultraviolet-visible spectrum. Uses In 1990, 45 thousand tonnes of isopropyl alcohol were used in the United States. The vast majority of isopropyl alcohol was used as a solvent for coatings or for industrial processes. Isopropyl alcohol in particular is popular for pharmaceutical applications, presumably due to the low toxicity of any residues. Some isopropyl alcohol is used as a chemical intermediate. Isopropyl alcohol may be converted to acetone, but the cumene process is more significant. In that year, a tiny fraction (5.4 tonnes) was consumed for household use and in personal care products. It is also used as a gasoline additive. Solvent Isopropyl alcohol dissolves a wide range of non-polar compounds. It also evaporates quickly and is relatively non-toxic, compared to alternative solvents. Thus it is used widely as a solvent and as a cleaning fluid, especially for dissolving oils. Together with ethanol, n-butanol, and methanol, it belongs to the group of alcohol-based solvents, about 6.4 million tonnes of which were utilized worldwide in 2011. Examples of this application include cleaning electronic devices such as contact pins (like those on ROM cartridges), magnetic tape and disk heads (such as those in audio and video tape recorders and floppy disk drives), the lenses of lasers in optical disc drives (e.g. CD, DVD) and removing thermal paste from heatsinks and IC packages (such as CPUs. Isopropyl alcohol is used in keyboard, LCD and laptop cleaning, is sold commercially as a whiteboard cleaner, and is a strong but safer alternative to common household cleaning products. It is commonly used to clean prepared optical fibers just before splicing. It is used to clean LCD and glass computer monitor screens (at some risk to the anti-reflection coating on some screens[citation needed]), and used to give second-hand or worn non-vinyl phonograph records newer-looking sheen. It is effective at removing Hot-Melt Adhesive from a large variety of surfaces. Isopropyl alcohol should not be used to clean vinyl records as it may leach plasticizer from the vinyl making it more rigid[citation needed]. It is effective at removing residual glue from some sticky labels although some other adhesives used on tapes and paper labels are resistant to it. It can also be used to remove stains from most fabrics, wood, cotton, etc. In addition it can also be used to clean paint or other oil based products so that they may be reused, commonly known as "repainting." It is used as a wetting agent in the fountain solution used in lithographic printing, and often used as a solvent for French polishing shellac used in cabinet making. Intermediate Isopropyl alcohol is esterified to give isopropyl acetate, another solvent. It reacts with carbon disulfide and sodium hydroxide to give sodium isopropylxanthate, a herbicide and an ore flotation reagent. Isopropyl alcohol reacts with titanium tetrachloride and aluminium metal to give titanium and aluminium isopropoxides respectively, the former a catalyst, and the latter a chemical reagent. This compound may serve as a chemical reagent in itself, by acting as a dihydrogen donor in transfer hydrogenation. Medical Disinfecting pads typically contain a 60–70% solution of isopropyl alcohol in water. A 75% v/v solution in water may be used as a hand sanitizer.[14] Isopropyl alcohol is used as a water-drying aid for the prevention of otitis externa, better known as swimmer's ear. Early uses as an anesthetic Although isopropanol can be technically used for anesthesia, its many negative drawbacks prohibit this use. Isopropanol can also be used similar to ether as a solvent[16] or anesthesia by inhaling the fumes or orally. Early uses included using the solvent as general anesthesia for small mammals and rodents by scientists and some veterinarians. However, it was soon discontinued as many complications arose including respiratory irritation, internal bleeding, visual and hearing problems. In rare cases, respiratory failure leading to death in animals was observed. Like ether, isopropanol is also very volatile and due to their medical complications, both are prohibited to be used for either human or animal uses, either lab or medical unless approved by IACC.[citation needed Automotive Isopropyl alcohol is a major ingredient in "gas dryer" fuel additives. In significant quantities, water is a problem in fuel tanks, as it separates from the gasoline, and can freeze in the supply lines at cold temperatures. It does not remove water from gasoline; rather, the alcohol solubilizes water in gasoline. Once soluble, water does not pose the same risk as insoluble water as it will no longer accumulate in the supply lines and freeze. Isopropyl alcohol is often sold in aerosol cans as a windshield de-icer. Isopropyl alcohol is also used to remove brake fluid traces from hydraulic braking systems, so that the brake fluid (usually DOT 3, DOT 4 or mineral oil) does not contaminate the brake pads, which would result in poor braking. Laboratory As a biological specimen preservative, isopropyl alcohol provides a comparatively non-toxic alternative to formaldehyde and other synthetic preservatives. Isopropyl alcohol solutions of 70–99% are used to preserve specimens. Isopropyl alcohol is often used in DNA extraction. It is added to a DNA solution in order to precipitate the DNA into a 'pellet' after centrifuging the DNA. This is possible because DNA is insoluble in isopropyl alcohol. Isopropanol (IPA) is one of the most widely used solvents in the world; also used as a chemical intermediate. See Product Uses. IPA exposure is possible in both industrial and consumer applications. Occupational exposure limits have been established to control the allowable amount of exposure in workplace settings. Consumer exposure, generally infrequent and short in duration, is also highly dependent upon the conditions under which IPA is used. See Exposure Potential. IPA does not cause adverse health or environmental effects at levels typically found in the workplace or in the environment. Flammable with high vapor pressure; use good ventilation and avoid all ignition sources. See Physical Hazard Information. The largest use for IPA is as a solvent. The second largest use is as a chemical intermediate. IPA is also found in many everyday products such as paints, inks, general-purpose cleaners, disinfectants, room sprays and windshield deicing agents. IPA is commonly used in nitrocellulose-based lacquers and thinners for wood finishing, in adhesives, pharmaceuticals, cosmetics and toiletries, disinfectants, rubbing compounds, and lithography. It is also used as an ingredient in cleaners and polishers, as a chemical intermediate, and as a dehydrating agent and extractant. สอบถามข้อมูลเพิ่มเติมได้ที่ ฝ่ายขาย Thai Poly Chemicals Co., Ltd. บริษัท ไทยโพลีเคมิคอล จำกัด ที่อยู่36/5 ม.9 แขวง/ตำบลนาดี เขต/อำเภอเมืองสมุทรสาคร จังหวัดสมุทรสาคร รหัสไปรษณีย์74000 Tel.: 034854888, 034496284 Fax.: 034854899, 034496285 Mobile: 0824504888, 0800160016 Website : www.thaipolychemicals.com Email1 : thaipolychemicals@hotmail.com Eamil2 : info@thaipolychemicals.com
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